Monte Rosa Therapeutics, a biotechnology company, announced that Swiss pharmaceutical company Novartis will pay $150 million upfront for a global license to develop, manufacture, and commercialize certain drugs. This agreement includes a class of drugs known as “molecular glue degraders,” which target abnormal protein functions associated with diseases that are difficult to treat with existing medications. Monte Rosa is also eligible to receive up to $2.1 billion in future payments and royalties on sales outside the United States. Molecular glue degraders are small molecules that link a target protein to an enzyme responsible for tagging cellular components for disposal. Novartis will gain access to MRT-6160, a drug currently in early-stage studies by Monte Rosa for immune-mediated diseases, with mid-stage studies to be conducted by Novartis. citeturn0search0