{"id":1821,"date":"2025-09-16T08:18:03","date_gmt":"2025-09-16T08:18:03","guid":{"rendered":"https:\/\/sitefansalaran.ir\/En\/?p=1821"},"modified":"2025-09-16T08:18:03","modified_gmt":"2025-09-16T08:18:03","slug":"novartis-signs-up-to-5-7-billion-licensing-deal-with-monte-rosa-therapeutics","status":"publish","type":"post","link":"https:\/\/sitefansalaran.ir\/En\/2025\/09\/16\/novartis-signs-up-to-5-7-billion-licensing-deal-with-monte-rosa-therapeutics\/","title":{"rendered":"Novartis signs up to $5.7 billion licensing deal with Monte Rosa Therapeutics"},"content":{"rendered":"<p style=\"text-align: justify;\">Swiss drugmaker Novartis (NOVN.S), opens new tab and drug developer Monte Rosa Therapeutics (GLUE.O), opens new tab agreed to an up to $5.7 billion licensing deal to develop treatments for immune-related diseases, the companies said on Monday, marking their second partnership in less than a year.<\/p>\n<p style=\"text-align: justify;\">Under the agreement, Monte Rosa will receive $120 million upfront and could earn additional milestone payments and royalties.<br \/>\nShares of the Boston based company jumped 50% in early morning trading after the announcement.<\/p>\n<p style=\"text-align: justify;\">Immune-related diseases occur when the immune system mistakenly attacks healthy tissues, causing inflammation and damage. These hard-to-treat conditions can severely impact patients&#8217; quality of life.<\/p>\n<p style=\"text-align: justify;\">The deal grants Novartis exclusive rights to an undisclosed drug discovery target and options to license two additional programs from Monte Rosa\u2019s early stage immunology portfolio.<\/p>\n<p style=\"text-align: justify;\">The agreement represents &#8220;additional validation&#8221; of Monte Rosa&#8217;s molecular glue degrader discovery platform from an existing large pharma partner, Wedbush\u2019s Robert Driscoll said.<\/p>\n<p style=\"text-align: justify;\">Monte Rosa\u2019s platform, QuEEN, uses artificial intelligence and machine learning to discover and develop new degraders &#8211; small molecules designed to break down disease-causing proteins &#8211; which Novartis will take into clinical development and commercialisation.<\/p>\n<p style=\"text-align: justify;\">The deal allows Monte Rosa to leverage Novartis&#8217; development capabilities to drive programs forward, and use the cash to achieve important milestones with its wholly-owned pipeline, Driscoll added.<\/p>\n<p style=\"text-align: justify;\">Last year, the companies signed a similar $150 million upfront deal for MRT-6160, an early-stage autoimmune\/inflammatory drug, with potential future payments up to $2.1 billion plus royalties on non-U.S. sales.<\/p>\n<p style=\"text-align: justify;\">The agreement is Novartis\u2019 second major deal this month, after an up to $5.2 billion tie up with China\u2019s Argo Biopharmaceutical for experimental heart drugs.<\/p>\n<p style=\"text-align: justify;\">Monte Rosa shares had fallen about 31% year-to-date till Friday close.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Swiss drugmaker Novartis (NOVN.S), opens new tab and drug developer Monte Rosa Therapeutics (GLUE.O), opens new tab agreed to an up to $5.7 billion licensing deal to develop treatments for immune-related diseases, the companies said on Monday, marking their second partnership in less than a year. Under the agreement, Monte Rosa will receive $120 million [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1822,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[37],"tags":[498],"class_list":{"0":"post-1821","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-sitefansalaran-industry-news","8":"tag-novartis-signs-up-to-5-7-billion-licensing-deal-with-monte-rosa-therapeutics"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.7 (Yoast SEO v25.4) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Novartis signs up to $5.7 billion licensing deal with Monte Rosa Therapeutics - sitefansalarn<\/title>\n<meta name=\"description\" content=\"Novartis signs up to $5.7 billion licensing deal with Monte Rosa Therapeutics\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sitefansalaran.ir\/En\/2025\/09\/16\/novartis-signs-up-to-5-7-billion-licensing-deal-with-monte-rosa-therapeutics\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Novartis signs up to $5.7 billion licensing deal with Monte Rosa Therapeutics\" \/>\n<meta property=\"og:description\" content=\"Novartis signs up to $5.7 billion licensing deal with Monte Rosa Therapeutics\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sitefansalaran.ir\/En\/2025\/09\/16\/novartis-signs-up-to-5-7-billion-licensing-deal-with-monte-rosa-therapeutics\/\" \/>\n<meta property=\"og:site_name\" content=\"sitefansalarn\" \/>\n<meta property=\"article:published_time\" content=\"2025-09-16T08:18:03+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sitefansalaran.ir\/En\/wp-content\/uploads\/2025\/09\/photo_2025-09-16_11-49-13.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"975\" \/>\n\t<meta property=\"og:image:height\" content=\"618\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"dorost\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"dorost\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/sitefansalaran.ir\/En\/2025\/09\/16\/novartis-signs-up-to-5-7-billion-licensing-deal-with-monte-rosa-therapeutics\/\",\"url\":\"https:\/\/sitefansalaran.ir\/En\/2025\/09\/16\/novartis-signs-up-to-5-7-billion-licensing-deal-with-monte-rosa-therapeutics\/\",\"name\":\"Novartis signs up to $5.7 billion licensing deal with Monte Rosa Therapeutics - 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