{"id":1752,"date":"2025-09-14T16:43:48","date_gmt":"2025-09-14T16:43:48","guid":{"rendered":"https:\/\/sitefansalaran.ir\/En\/?p=1752"},"modified":"2025-09-14T16:43:48","modified_gmt":"2025-09-14T16:43:48","slug":"biontech-bristol-myers-immunotherapy-shows-encouraging-tumour-shrinkage-in-phase-ii-trial","status":"publish","type":"post","link":"https:\/\/sitefansalaran.ir\/En\/2025\/09\/14\/biontech-bristol-myers-immunotherapy-shows-encouraging-tumour-shrinkage-in-phase-ii-trial\/","title":{"rendered":"BioNTech, Bristol Myers&#8217; immunotherapy shows encouraging tumour shrinkage in Phase II trial"},"content":{"rendered":"<p style=\"text-align: justify;\">A next-generation cancer immunotherapy by BioNTech and partner Bristol Myers Squibb\u00a0(BMY.N), opens new tab\u00a0led to encouraging tumour shrinkage in a mid-stage trial on small cell lung cancer that has started spreading, the German biotech firm said on Monday.<\/p>\n<p style=\"text-align: justify;\">A Phase II trial showed that 76.3% of the 38 participants on the drug BNT327, also know as pumitamig, who qualified for an interim analysis saw their tumours shrink, BioNTech said in a statement.<\/p>\n<p style=\"text-align: justify;\">Keep up with the latest medical breakthroughs and healthcare trends with the<br \/>\ndemonstrated a manageable safety profile with no new safety concerns and a low rate of people dropping out due to side effects, it added.<\/p>\n<p style=\"text-align: justify;\">The drug is already being tested in a Phase III lung cancer trial.<\/p>\n<p style=\"text-align: justify;\">Bristol Myers in June\u00a0agreed\u00a0to pay up to $11.1 billion to collaborate with BioNTech on the experimental drug, betting on a next-generation cancer immunotherapy that could take on rival Merck &amp; Co&#8217;s best-selling drug Keytruda.<\/p>\n<p style=\"text-align: justify;\">Several rival companies are pursuing an approach similar to pumitamig, which is designed to activate the immune system &#8211; like the established drug class including Keytruda &#8211; but also to cut a tumour off from its blood supply.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A next-generation cancer immunotherapy by BioNTech and partner Bristol Myers Squibb\u00a0(BMY.N), opens new tab\u00a0led to encouraging tumour shrinkage in a mid-stage trial on small cell lung cancer that has started spreading, the German biotech firm said on Monday. A Phase II trial showed that 76.3% of the 38 participants on the drug BNT327, also know [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1753,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[37],"tags":[268,467],"class_list":{"0":"post-1752","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-sitefansalaran-industry-news","8":"tag-biontech","9":"tag-bristol-myers-immunotherapy-shows-encouraging-tumour-shrinkage-in-phase-ii-trial"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.7 (Yoast SEO v25.4) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>BioNTech, Bristol Myers&#039; immunotherapy shows encouraging tumour shrinkage in Phase II trial - sitefansalarn<\/title>\n<meta name=\"description\" content=\"BioNTech, Bristol Myers&#039; immunotherapy shows encouraging tumour shrinkage in Phase II trial\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sitefansalaran.ir\/En\/2025\/09\/14\/biontech-bristol-myers-immunotherapy-shows-encouraging-tumour-shrinkage-in-phase-ii-trial\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"BioNTech, Bristol Myers&#039; immunotherapy shows encouraging tumour shrinkage in Phase II trial\" \/>\n<meta property=\"og:description\" content=\"BioNTech, Bristol Myers&#039; immunotherapy shows encouraging tumour shrinkage in Phase II trial\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sitefansalaran.ir\/En\/2025\/09\/14\/biontech-bristol-myers-immunotherapy-shows-encouraging-tumour-shrinkage-in-phase-ii-trial\/\" \/>\n<meta property=\"og:site_name\" content=\"sitefansalarn\" \/>\n<meta property=\"article:published_time\" content=\"2025-09-14T16:43:48+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sitefansalaran.ir\/En\/wp-content\/uploads\/2025\/09\/photo_2025-09-14_20-14-49.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1248\" \/>\n\t<meta property=\"og:image:height\" content=\"832\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"dorost\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"dorost\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/sitefansalaran.ir\/En\/2025\/09\/14\/biontech-bristol-myers-immunotherapy-shows-encouraging-tumour-shrinkage-in-phase-ii-trial\/\",\"url\":\"https:\/\/sitefansalaran.ir\/En\/2025\/09\/14\/biontech-bristol-myers-immunotherapy-shows-encouraging-tumour-shrinkage-in-phase-ii-trial\/\",\"name\":\"BioNTech, Bristol Myers' immunotherapy shows encouraging tumour shrinkage in Phase II trial - 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